Remodeling of the Extracellular Matrix by Endothelial Cell-Targeting siRNA Improves the EPR-Based Delivery of 100 nm Particles.
作者： Yu Sakurai , Tomoya Hada , Shoshiro Yamamoto , Akari Kato , Wataru Mizumura
DOI: 10.1038/MT.2016.178
关键词:
摘要: … to the intratumoral diffusion of cancer-targeted nanoparticles. The high density of cells, in … regulating the tumor microenvironment via inhibiting VEGFR2 allows even large nanoparticles …
core.ac.uk 
sci-hub.se 参考文章(50)
Agnieszka Blazejczyk, Diana Papiernik, Kseniia Porshneva, Joanna Sadowska, Joanna Wietrzyk, Endothelium and cancer metastasis: Perspectives for antimetastatic therapy Pharmacological Reports. ,vol. 67, pp. 711- 718 ,(2015) , 10.1016/J.PHAREP.2015.05.014
Strategies to improve the EPR effect for the delivery of anti-cancer nanomedicines Cancer cell & microenvironment. ,vol. 2, ,(2015) , 10.14800/CCM.808
Robert E. Neuman, Milan A. Logan, The determination of collagen and elastin in tissues. Journal of Biological Chemistry. ,vol. 186, pp. 549- 556 ,(1950) , 10.1016/S0021-9258(18)56248-7
Moungi G. Bawendi, Triantafyllos Stylianopoulos, Sergey V. Kozin, Delphine A. Lacorre, John Daniel Martin, Zoran Popovic, Xiaoxing Han, Peigen Huang, Yves Boucher, Rakesh K. Jain, Vikash P. Chauhan, Ahmed S. Mousa, Saloni R. Jain, Pichet Adstamongkonkul, Hao Liu, Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels PMC. ,(2013)
Tomoya Hada, Yu Sakurai, Hideyoshi Harashima, Optimization of a siRNA Carrier Modified with a pH-Sensitive Cationic Lipid and a Cyclic RGD Peptide for Efficiently Targeting Tumor Endothelial Cells Pharmaceutics. ,vol. 7, pp. 320- 333 ,(2015) , 10.3390/PHARMACEUTICS7030320
Elena Ongaro, Silvia Bolzonello, Caterina Fontanella, Giuseppe Aprile, Gianpiero Fasola, Michela Guardascione, Clinical advances in the development of novel VEGFR2 inhibitors Annals of Translational Medicine. ,vol. 2, pp. 123- 123 ,(2014) , 10.3978/J.ISSN.2305-5839.2014.08.14
Hiral Parekh, Brian I Rini, Emerging therapeutic approaches in renal cell carcinoma. Expert Review of Anticancer Therapy. ,vol. 15, pp. 1305- 1314 ,(2015) , 10.1586/14737140.2015.1090315
Laurie D. DeLeve, Liver sinusoidal endothelial cells in hepatic fibrosis. Hepatology. ,vol. 61, pp. 1740- 1746 ,(2015) , 10.1002/HEP.27376
Surim Park, Jong Won Kim, Jong Hoon Kim, Chae Woong Lim, Bumseok Kim, Differential Roles of Angiogenesis in the Induction of Fibrogenesis and the Resolution of Fibrosis in Liver. Biological & Pharmaceutical Bulletin. ,vol. 38, pp. 980- 985 ,(2015) , 10.1248/BPB.B15-00325
D. Robert Siemens, Jeremy P.W. Heaton, Michael A. Adams, Jun Kawakami, Charles H. Graham, Phase II study of nitric oxide donor for men with increasing prostate-specific antigen level after surgery or radiotherapy for prostate cancer. Urology. ,vol. 74, pp. 878- 883 ,(2009) , 10.1016/J.UROLOGY.2009.03.004