Engineered microbial systems for enhanced conversion of lignocellulosic biomass

摘要: In order for plant biomass to become a viable feedstock meeting the future demand liquid fuels, efficient and cost-effective processes must exist breakdown cellulosic materials into their primary components. A one-pot conversion strategy or, consolidated bioprocessing, of ethanol would provide most route renewable fuels realization this technology is being actively pursued by both multi-disciplinary research centers industrialists working at very cutting edge field. Although diverse range bacteria fungi possess enzymatic machinery capable hydrolyzing plant-derived polymers, none discovered so far meet requirements an industrial strength biocatalyst direct combustible fuels. Synthetic biology combined with better fundamental understanding cellulose hydrolysis molecular level enabling rational engineering microorganisms utilizing simultaneous fuel.