Improved adherence and anaemia cure rates with flexible administration of micronutrient Sprinkles: a new public health approach to anaemia control

摘要: Despite repeated public commitments and availability of various forms iron supplements, rates anaemia in developing countries remain high. A major reason for this lack success has been poor adherence. The objective study was to compare the effectiveness daily flexible administration micronutrient Sprinkles on adherence, acceptability haematological status among young children rural Bangladesh. sample 362 (haemoglobin (Hb)⩾70 g l−1) aged 6–24 months were cluster-randomized receive 60 sachets either (i) over 2 months; (ii) flexibly 3 or (iii) 4 months. With a regimen, mothers/caregivers decided how frequently use without exceeding one sachet per day. Adherence assessed monthly by counting number used evaluated through focus group discussions. Haemoglobin measured at baseline, end each intervention period 6 post-intervention. Mean percent adherence significantly higher flexible-4-month (98%) compared flexible-3-month (93%) daily-2-month (88%) groups (P<0.01). Most mothers found be more acceptable than due perceived benefits use. Hb (P=0.03). Anaemia prevalence decreased 65% 54% 51% groups. Percent cured who maintained non-anaemic post-intervention (82%) (80%) (53%) (P<0.05). response preferable daily.