作者: Junichi Kikuta , Tetsuro Tabata , Toshihiro Shimizu
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摘要: An effervescent composition comprising a core-shell powder consisting of fine granular core spray-coated with liquid mixture containing water-soluble polymer such as hydroxypropylcellulose or hydroxypropylmethylcellulose, and at least one physiologically active substance, especially an acid-sensitive drugs, enteric coating film, effervescing component auxiliary agent which provides for controlled release the substance in useful preparing uniform solution suspension having refreshing sensation on ingestion.