Alcohol Increases Aggression in Flies
作者： Annie Park , Tracy Tran , Elizabeth Scheuermann , Linda Gutierrez , Christopher Stojanik
DOI: 10.1101/685529
关键词:
摘要: Abstract Alcohol-induced aggression is a destructive and widespread phenomenon, but we understand very little about the mechanisms that produce this behavior. We found two different alcohol exposures potentiate in male flies. (1) A pharmacologically relevant dose of increases decreases goal-directed behavior (2) In addition, odor itself enhances intermale by potentiating olfactory signaling cis-vaccenyl acetate (cVa), volatile pheromone. Characterizing these behaviors genetically tractable fruit fly can lead to better understanding molecular correlates regulate alcohol-induced humans provide insights into an ethologically One Sentence Summary identified pathways through which stimulates flies; one acts pheromone while other mediated systemic effects alcohol.
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