Tuberculin skin test versus interferon-gamma release assays for the diagnosis of tuberculosis infection.
作者： E. De Keyser , F. De Keyser , F. De Baets
DOI: 10.1179/2295333714Y.0000000043
关键词:
摘要: AbstractObjective:Accurate detection of latent tuberculosis infection (LTBI) is becoming increasingly important due to the increasing use immunosuppressive medications and human immunodeficiency epidemic, which have increased risk for reactivation active (TB) infection. LTBI detected by tuberculin skin test (TST) interferon-gamma release assays (IGRAs). The latter include T-SPOT®.TB (Oxford Immunotec) QuantiFERON®-TB Gold In-Tube (QFT-GIT; Cellestis). We examined value TST versus IGRAs in diagnosis TB meta-analysis based on data derived from a systematic literature review.Methods:PubMed was searched articles English published between January 2010 July 2012 IGRA were performed simultaneously individuals with without A random effect model determine pooled sensitivity specificity values TST, T-SPOT.TB, QFT-GIT. Owing absence gold stand...
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