Polarized light (λ400-2000 nm) on third-degree burns in diabetic rats: immunohistochemical study.
作者： Priscila Chagas Oliveira , Antônio Luiz Barbosa Pinheiro , João Alves Reis Junior , Isabelle C.V. de Castro , Clarissa Gurgel
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摘要: Abstract Aim: The aim of this study was to evaluate with light microscopy the healing process third-degree burns on diabetic rats treated polarized (λ400–2000 nm, 20 or 40 J/cm2/session, 40 mW/cm2, 2.4 J/cm2/min, 5.5-cm beam diameter). Background: Uncontrolled diabetes mellitus causes severe disruption body's metabolism, including healing. Polarized sources have been shown be effective in improving many situations. Animals and Methods: Diabetes induced streptozotocin (60 mg/kg) 45 male Wistar albino rats, a burn (1.5 by 1.5 cm) created dorsum each animal under general anesthesia. animals were randomly distributed into three groups: control, 20 J/cm2, 40 J/cm2. Each group then divided subgroups based time death (7, 14, 21 d). Phototherapy (20 40 J/cm2 per session) carried out immediately after burning repeated daily until day before death. Following death, spec...
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