Trimerization of a yeast transcriptional activator via a coiled-coil motif
作者： Peter K. Sorger , Hillary C.M. Nelson
DOI: 10.1016/0092-8674(89)90604-1
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摘要: The transcriptional induction of heat shock genes is mediated by the transcription factor (HSF). We have investigated oligomerization state HSF from S. cerevisiae and find that it forms a trimer in solution when bound to DNA. Trimerization region that, like leucine zipper, characterized occurrence hydrophobic amino acids every 7 residues. propose three-stranded coiled coil.
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