Morphology and function: MR pineal volume and melatonin level in human saliva are correlated

摘要: Purpose To investigate the relation between circadian saliva melatonin levels and pineal volume as determined by MRI. Plasma follow a rhythm with high interindividual variability. Materials Methods In 103 healthy individuals were at four time points within 24 h MRI was performed once (3.0 Tesla, including three-dimensional T2 turbo spin echo [3D-T2-TSE], susceptibility-weighted imaging [SWI]). Pineal well cyst assessed from multiplanar reconstructed 3D-T2-TSE images. calcification tissue on SWI. To correct for hormonal inactive tissue, cystic calcified areas excluded. Sleep quality Landeck Inventory sleep disturbance. Results Solid uncalcified correlated to maximum (r = 0.28; P < 0.05) area under curve (r = 0.29; P < 0.05). Of interest, solid negatively disturbances subscore (r = −0.17; despite very homogenous population. Conclusion Uncalcified measured SWI is related human levels. The analysis of suggests linkage better active tissue. J. Magn. Reson. Imaging 2014;40:966–971. © 2013 Wiley Periodicals, Inc.