Clinical characteristics of bladder cancer in patients previously treated with radiation for prostate cancer

摘要: OBJECTIVE To determine if bladder cancer diagnosed after prostatic radiation therapy (RT) differs in behaviour from prostate not treated with RT, as such is thought to be more aggressive than de novo cancer, and epidemiological studies show a higher rate of patients irradiation. PATIENTS AND METHODS We reviewed our records identify who had diagnosis previous cancer. Patient age, date symptoms, clinical stage, initial pathology, definitive therapy, pathological disease status were recorded. RESULTS In all, 100 identified between January 1992 August 2003; 58 RT for The mean time was 62 months the group 34 months unirradiated (P = 0.002) At 56 (97%) received high-grade urothelial carcinoma, vs 27 (64%) those irradiated (P < 0.001). Thirty (52%) muscle-invasive 17 (40%) (P = 0.3). survival similar both groups. CONCLUSIONS Bladder later, grade, are other methods. Patients should monitored closely presence