Induced pluripotent stem (iPS) cells from human fetal stem cells.
DOI: 10.1016/J.BPOBGYN.2015.08.007
关键词:
摘要: Pluripotency defines the ability of stem cells to differentiate into all lineages three germ layers and self-renew indefinitely. Somatic can regain developmental potential embryonic following ectopic expression a set transcription factors or, in certain circumstances, via modulation culture conditions supplementation with small molecule, that is, induced pluripotent (iPS) cells. Here, we discuss use fetal tissues for reprogramming, focusing particular on derived from human amniotic fluid, development chemical reprogramming. We next address advantages disadvantages deriving clinical applications.
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