Expression of ATM protein and its relationship with p53 in pancreatic carcinoma with tissue array.
作者： Guanzhen Yu , Ming-hua Zhu , Zhi Zhu , Can-rong Ni , Jian-ming Zheng
DOI: 10.1097/00006676-200405000-00011
关键词:
摘要: Abstract:ATM protein anticipates in the initiation of DNA repair signal pathway and also mediates cell cycle arrest repair. ATM deficiency predictably results radiosensitivity, germ degeneration, chromosomal instability, immunodeficiency, an extreme predisposition to tumors. More
sci-hub.se 参考文章(22)
AM Taylor, JA Metcalfe, J Thick, YF Mak, Leukemia and lymphoma in ataxia telangiectasia Blood. ,vol. 87, pp. 423- 438 ,(1996) , 10.1182/BLOOD.V87.2.423.BLOODJOURNAL872423
Andrew R. Pettitt, Paul D. Sherrington, Grant Stewart, John C. Cawley, A. Malcolm R. Taylor, Tatjana Stankovic, p53 dysfunction in B-cell chronic lymphocytic leukemia: inactivation of ATM as an alternative toTP53 mutation Blood. ,vol. 98, pp. 814- 822 ,(2001) , 10.1182/BLOOD.V98.3.814
Carmen Rodriguez, Hélène Vallès, Annick Causse, Vala Johannsdottir, Jean-François Eliaou, Charles Theillet, Involvement of ATM missense variants and mutations in a series of unselected breast cancer cases. Genes, Chromosomes and Cancer. ,vol. 33, pp. 141- 149 ,(2002) , 10.1002/GCC.1222
Kum Kum Khanna., Katherine E. Keating, Sergei Kozlov, Shaun Scott, Magtouf Gatei, Karen Hobson, Yoichi Taya, Brian Gabrielli, Doug Chan, Susan P. Lees-Miller, Martin F. Lavin, ATM associates with and phosphorylates p53: mapping the region of interaction Nature Genetics. ,vol. 20, pp. 398- 400 ,(1998) , 10.1038/3882
Shin'ichi Saito, Aaron A. Goodarzi, Yuichiro Higashimoto, Yuka Noda, Susan P. Lees-Miller, Ettore Appella, Carl W. Anderson, ATM Mediates Phosphorylation at Multiple p53 Sites, Including Ser46, in Response to Ionizing Radiation Journal of Biological Chemistry. ,vol. 277, pp. 12491- 12494 ,(2002) , 10.1074/JBC.C200093200
G. C. M. Smith, R. B. Cary, N. D. Lakin, B. C. Hann, S.-H. Teo, D. J. Chen, S. P. Jackson, Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 96, pp. 11134- 11139 ,(1999) , 10.1073/PNAS.96.20.11134
Carolyn H. Buzin, Richard A. Gatti, Vu Q. Nguyen, Cindy Y. Wen, Midori Mitui, Ozden Sanal, Jie Sheng Chen, Guity Nozari, April Mengos, Xuemin Li, Frank Fujimura, Steve S. Sommer, Comprehensive scanning of the ATM gene with DOVAM-S. Human Mutation. ,vol. 21, pp. 123- 131 ,(2003) , 10.1002/HUMU.10158
Tatjana Stankovic, GS Stewart, Philip Byrd, C Fegan, PAH Moss, AMR Taylor, None, ATM mutations in sporadic lymphoid tumours. Leukemia & Lymphoma. ,vol. 43, pp. 1563- 1571 ,(2002) , 10.1080/1042819021000002884
Eli Berkovich, Doron Ginsberg, ATM is a target for positive regulation by E2F-1. Oncogene. ,vol. 22, pp. 161- 167 ,(2003) , 10.1038/SJ.ONC.1206144
Andreas Waha, Chris Sturne, Astrid Kessler, Anke Koch, Ellen Kreyer, Rolf Fimmers, Otmar D. Wiestler, Andreas von Deimling, Dieter Krebs, Rita K. Schmutzler, Expression of theATM gene is significantly reduced in sporadic breast carcinomas International Journal of Cancer. ,vol. 78, pp. 306- 309 ,(1998) , 10.1002/(SICI)1097-0215(19981029)78:3<306::AID-IJC8>3.0.CO;2-Z