Elabela protects against podocyte injury in mice with streptozocin-induced diabetes by associating with the PI3K/Akt/mTOR pathway.
作者： Yixian Zhang , Yangwei Wang , Manyu Luo , Feng Xu , Yue Lu
DOI: 10.1016/J.PEPTIDES.2019.04.005
关键词:
摘要: … prevent diabetes-induced podocyte foot process … cell apoptosis and promotes cell differentiation and survival, which plays an important role in the prevention and treatment of diabetes […
sci-hub.se 参考文章(34)
Li Zhou, Hong Xue, Ping Yuan, Jun Ni, Chen Yu, Yu Huang, Li-Min Lu, Angiotensin AT1 receptor activation mediates high glucose-induced epithelial-mesenchymal transition in renal proximal tubular cells. Clinical and Experimental Pharmacology and Physiology. ,vol. 37, ,(2010) , 10.1111/J.1440-1681.2010.05421.X
Cheng Deng, Haidi Chen, Na Yang, Yi Feng, Aaron J. W. Hsueh, Apela Regulates Fluid Homeostasis by Binding to the APJ Receptor to Activate Gi Signaling Journal of Biological Chemistry. ,vol. 290, pp. 18261- 18268 ,(2015) , 10.1074/JBC.M115.648238
Lena Ho, Shawn Y.X. Tan, Sheena Wee, Yixuan Wu, Sam J.C. Tan, Navin B. Ramakrishna, Serene C. Chng, Srikanth Nama, Iwona Szczerbinska, Yun-Shen Chan, Stuart Avery, Norihiro Tsuneyoshi, Huck Hui Ng, Jayantha Gunaratne, N. Ray Dunn, Bruno Reversade, ELABELA Is an Endogenous Growth Factor that Sustains hESC Self-Renewal via the PI3K/AKT Pathway Cell Stem Cell. ,vol. 17, pp. 435- 447 ,(2015) , 10.1016/J.STEM.2015.08.010
Hamid Najafipour, Ava Soltani Hekmat, Ali Akbar Nekooian, Saeed Esmaeili-Mahani, Apelin receptor expression in ischemic and non- ischemic kidneys and cardiovascular responses to apelin in chronic two-kidney-one-clip hypertension in rats. Regulatory Peptides. ,vol. 178, pp. 43- 50 ,(2012) , 10.1016/J.REGPEP.2012.06.006
Serene C. Chng, Lena Ho, Jing Tian, Bruno Reversade, ELABELA: a hormone essential for heart development signals via the apelin receptor Developmental Cell. ,vol. 27, pp. 672- 680 ,(2013) , 10.1016/J.DEVCEL.2013.11.002
Juan F. Navarro-González, Carmen Mora-Fernández, Mercedes Muros de Fuentes, Javier García-Pérez, Inflammatory molecules and pathways in the pathogenesis of diabetic nephropathy Nature Reviews Nephrology. ,vol. 7, pp. 327- 340 ,(2011) , 10.1038/NRNEPH.2011.51
Séverine Roselli, Olivier Gribouval, Nicolas Boute, Mireille Sich, France Benessy, Tania Attié, Marie-Claire Gubler, Corinne Antignac, Podocin localizes in the kidney to the slit diaphragm area. American Journal of Pathology. ,vol. 160, pp. 131- 139 ,(2002) , 10.1016/S0002-9440(10)64357-X
Javier Donate-Correa, Ernesto Martín-Núñez, Mercedes Muros-de-Fuentes, Carmen Mora-Fernández, Juan F. Navarro-González, Inflammatory Cytokines in Diabetic Nephropathy Experimental Diabetes Research. ,vol. 2015, pp. 948417- 948417 ,(2015) , 10.1155/2015/948417
C.E. Mogensen, Microalbuminuria as a predictor of clinical diabetic nephropathy Kidney International. ,vol. 31, pp. 673- 689 ,(1987) , 10.1038/KI.1987.50
J NAVARRO, C MORAFERNANDEZ, The role of TNF-α in diabetic nephropathy: Pathogenic and therapeutic implications Cytokine & Growth Factor Reviews. ,vol. 17, pp. 441- 450 ,(2006) , 10.1016/J.CYTOGFR.2006.09.011