Bile Acids in Hepato-Biliary Diseases

摘要: Bile acids are the end products of hepatic cholesterol metabolism. They conjugated to taurine and glycine excreted with bile into intestine where they reabsorbed again accumulated in liver via portal system. This enterohepatic circulation is well demonstrated but only little known on mechanisms involved transport through membranes cells during uptake from blood excretion bile. Blood easily available ample information exists these two compartments acid pool, whereas less acids. Since almost all metabolic reactions formation conjugation mediated by enzymes, changes composition can be expected diseases. Information presently data concerning such consequences thereof presented subsequently.