Comparative Effects of Ovariectomy and Flutamid on Body-Uterus Weight and Uterine Histology in the Ovariectomized Rat Model+ -

作者: Nurullah Özdemir , Berna Güney Saruhan , Davut Özbað , Yakup Gümüþalan

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摘要: Objective: To determine the effect of flutamide on uterine histology and to ascertain whether regulates body weight gain in ovariectomized rat model. Materials Methods: We used 36 sexually mature female Wistar-Albino rats this study. The study was performed Department Medical Science Application Research Centre Dicle University, Diyarbakir. divided model into 3 groups: group 1- control group, 2- sham-operated 3bilaterally group. In addition, we gave 3. Results: found that higher than rats, unlike decreased net weight. Furthermore, slightly after therapy, however increased. After applications, length uterinal epithelium, number glands, infiltration stromal cells increased lumen glands were dilateded. Conclusion: As a result, an improvement observed applications while bilateral ovariectomy determined cause atrophy epithelium rat. Our may be source for further research examining relationship between androgen receptor antagonist reproductive function rats.

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