The relationship between primary progressive aphasia and neurodegenerative dementia

摘要: Objective: To examine the relationship between primary progressive aphasia (PPA) and neurodegenerative dementia. Methods: Subjects were selected from 1723 consecutive patients who had undergone a medical examination at Kumamoto University Hospital Dementia Clinic, Japan, April 2007 to October 2012. First, with semantic dementia (SD) non-fluent diagnosed by clinical diagnostic criteria for frontotemporal lobar degeneration. Next, in same cohort, PPA according recent international consensus criteria. The symptoms including language psychiatric each patient group then compared. Results: In all, 12 of 27 SD fulfilled both variant (SD+PPA+ group), whereas other 15 met could not be included due prominent behavioural disturbances (SD+PPA- group). No significant differences characteristics functions found these 2 groups. Neuropsychiatric more severe SD+PPA- group. Conclusion: results suggest possibility that may identical, regardless different severities disturbance. When considering disorder dementia, it important diagnose subtype has than emphasise isolated deficits.