Altered brain diagnostic techniques in obesity and related metabolic complications

摘要: Abstract The prevalence of obesity has been increased in both developed and developing countries during the last decades. Low grade inflammation, insulin leptin resistance, endothelial dysfunction are some obesity-associated metabolic abnormalities, which have proposed to affect structure function brain. brain alternations recognized using diagnostic methods like EEG, PET MRI few studies. inflammation increase pro-inflammatory factors could impact size activity regions. Neurological studies also that resistance can alter results these techniques due changes entry Endothelial blood-brain barrier result microvascular permeability impaired microcirculatory blood flow CNS, influences obesity. effect related complications such as low on reflected by tests including structural functional MRI, PET. More neurological needed recognize relationship between obesity, body fat distribution, weight loss with assessed available techniques. This field study reveal other mechanisms involved pathogenesis, potential treatment opportunities.