Endogenous cholecystokinin reduces vocalization in isolated 10-day-old rats.

摘要: Devazepide, the cholecystokinin (CCK) A receptor blocker, markedly and specifically affected behavior of 10-day-old rats isolated from their mother siblings. Whereas intraoral infusions milk or fat, which cause CCK release, calmed infants, that is, reduced levels ultrasonic vocalization, devazepide fully blocked this reduction. Devazepide did not affect calming caused by sucrose infusions, do release CCK. Moreover, reduce elevated pain limen fat infusions. These data parallel earlier findings obtained with administration exogenous implicate endogenous in maintenance infant steady state calm. The possibility contributes to normal development mother-infant affectional systems is discussed.