Lectin-mediated drug targeting: preparation, binding characteristics, and antiproliferative activity of wheat germ agglutinin conjugated doxorubicin on Caco-2 cells.
作者： Michael Wirth , Andrea Fuchs , Michaela Wolf , Bernhard Ertl , Franz Gabor
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摘要: … to the tumor tissue, the objective of this work was the preparation and characterization of WGAconjugated DOX via an acid labile cis-aconityl linkage. The in vitro release of doxorubicin (…
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