Red Blood Cell Substitutes: Past, Present, and Future

摘要: Polyhemoglobin is already well into the final stages of clinical trials in humans. One has been approved for routine use South Africa. Perfluorochemicals are chemical oxygen carriers that being actively developed with some advanced trials. Meanwhile, new generations modified Hb can modulate effects nitric oxide. Other systems also to include antioxidant properties those applications may have potential problems related radicals. products animal testing based on hemoglobin-lipid vesicles, heme-albumin and heme-lipid vesicles. A further development nanotechnology biodegradable copolymers prepare nano-dimension artificial red blood cells containing hemoglobin complex enzyme systems.