Use of nasopharyngeal isolates of Streptococcus pneumoniae and Haemophilus influenzae from children in Pakistan for surveillance for antimicrobial resistance.

摘要: Antimicrobial resistance of Streptococcus pneumoniae and Haemophilus influenzae presents a challenge to clinical case management, particularly in programs for acute respiratory tract infection (ARI), including pneumonia, developing countries. To determine whether nasopharyngeal isolates S. H. from clinically defined group children could be used predict the prevalence antimicrobial strains that cause disease, 601 urban with ARI, 133 healthy 285 rural were evaluated Pakistan. Of 216 (35.9%) bacteremic, predominantly (108 children) (100 children). Overall 631 (61.9%) carried 381 (37.4%) influenzae. The proportions both organisms ARI resistant penicillin or ampicillin, trimethoprim/sulfamethoxazole, chloramphenicol erythromycin similar blood isolates. Nasopharyngeal had lower rates some agents. These findings suggest can conduct surveillance geographic area. Such would aid countries making rational choice agents use management bacterial diseases, pneumonia.