作者: Inês Falcão-Pires , Adelino F. Leite-Moreira
DOI: 10.1007/978-3-319-08798-6_19
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摘要: Cardiovascular diseases (CVD) often lead to heart failure (HF). HF prevalence is continuously rising and represents one of the leading causes death an economic burden in western societies. The study potential novel therapeutic options interventions requires reliable animal models evaluate myocardial progressive structural functional changes. Indeed, during past 40 years, basic translational scientists have used small understand pathophysiology improve prevention treatment patients suffering from congestive (CHF). Each species model has advantages disadvantages choice over another should take them into account for a good experimental design.