Modified lithium aluminum hydrides

作者: Norihiko Tanno , Kenji Koga , Shiro Terashima

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摘要: ABSTRACT OF THE DISCLOSURE: Novel modified lithium aluminum hydride type reducing agents obtained by reacting one equivalent of with an opti-cally active N-substituted ephedrine the formula, wherein R1 is a C1 - C4 alkyl group or benzyl group, and Ph phenyl group) two equivalents aniline (wherein R2 group). This agent usable for organic compounds having carbonyl (ketone aldehyde in their structure into corresponding alcohols. It particularly useful as asymmetrically unsym-metrical ketones to selectively produce either alco-hol which asymmetric carbon atom bonded hydroxy R-configuration alcohol said S-configuration.

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