Novel 2-arylbenzofuran dimers and polyisoprenylated flavanones from Sophora tonkinensis

作者: Guoyong Luo , Yun Yang , Min Zhou , Qi Ye , Yan Liu

DOI: 10.1016/J.FITOTE.2014.08.019

关键词:

摘要: Two novel 2-arylbenzofuran dimers, shandougenines A (1) and B (2), two new polyisoprenylated flavanones 3 (shandougenine C) 4 D) were isolated from the 95% EtOH extract of Sophora tonkinensis, together with 18 known compounds. Their structures determined on basis spectral data interpretation by comparing that reported previously for Shandougenine is a unique dimeric C-3C-5‴ bond linkage. (2) first naturally occurring C-3C-3″ Compound 1 showed moderate DPPH free radical scavenging capacity, whereas 2 has stronger ABTS cation capacity than Vc. Compounds 12, 19, 20 parallel 1, 3, 4, 20, 22 have to slightly superoxide anion flavanone luteolin. The antioxidant activities indicated compounds may represent scaffolds development antioxidants.

参考文章(35)
Dewu Zhang, Yan Ren, Shengjun Dai, Wanhui Liu, Guihai Li, None, Isoflavones from vines of Pueraria lobata China Journal of Chinese Matera Medica. ,vol. 34, pp. 3217- 3220 ,(2009)
Peilan Ding, Daofeng Chen, Isoprenylated Flavonoids from the Roots and Rhizomes of Sophora tonkinensis Helvetica Chimica Acta. ,vol. 89, pp. 103- 110 ,(2006) , 10.1002/HLCA.200690000
Paul Erasto, Gomotsang Bojase-Moleta, Runner R.T Majinda, Antimicrobial and antioxidant flavonoids from the root wood of Bolusanthus speciosus Phytochemistry. ,vol. 65, pp. 875- 880 ,(2004) , 10.1016/J.PHYTOCHEM.2004.02.011
Peramaiyan Rajendran, Natarajan Nandakumar, Thamaraiselvan Rengarajan, Rajendran Palaniswami, Edwinoliver Nesamony Gnanadhas, Uppalapati Lakshminarasaiah, Jacob Gopas, Ikuo Nishigaki, Antioxidants and human diseases. Clinica Chimica Acta. ,vol. 436, pp. 332- 347 ,(2014) , 10.1016/J.CCA.2014.06.004
Hermann Wegner, Mathieu Auzias, Markus Neuburger, 3,3 `-Bis(arylbenzofurans) via a Gold-Catalyzed Domino Process Synlett. ,vol. 2010, pp. 2443- 2448 ,(2010) , 10.1055/S-0030-1258566
Mingyu Sun, Hongyan Cao, Lin Sun, Shu Dong, Yanqin Bian, Jun Han, Lijun Zhang, Shuang Ren, Yiyang Hu, Chenghai Liu, Lieming Xu, Ping Liu, Antitumor Activities of Kushen: Literature Review Evidence-based Complementary and Alternative Medicine. ,vol. 2012, pp. 373219- 373219 ,(2012) , 10.1155/2012/373219
Pei-Lan Ding, Hai Huang, Pei Zhou, Dao-Feng Chen, Quinolizidine alkaloids with anti-HBV activity from Sophora tonkinensis. Planta Medica. ,vol. 72, pp. 854- 856 ,(2006) , 10.1055/S-2006-946639
Jin Jung, Sam Sik Kang, Ju Jung Woo, Jae Sue Choi, A new lavandulylated flavonoid with free radical and ONOO- scavenging activities from Sophora flavescens. Archives of Pharmacal Research. ,vol. 28, pp. 1333- 1336 ,(2005) , 10.1007/BF02977897
Mandar Deodhar, David StC. Black, Daniel Shiu-Hin Chan, Naresh Kumar, Synthesis of Some New Biheterocycles by a One-Pot Suzuki—Miyaura Coupling Reaction ChemInform. ,vol. 41, ,(2010) , 10.1002/CHIN.201033094