Repeat hepatectomy for recurrent colorectal liver metastases.

摘要: Purpose Liver resection represents the best and potentially curative treatment for metastatic colorectal cancer (MCC) to liver. After resection, however, most patients develop recurrent disease, often isolated The aim of this study was determine value repeat liver MCC analyze factors that can predict survival. Patients Methods From January 1992 October 2002, 42 from a group 168 resected were submitted 55 hepatectomies (42 second, 11 third, 2 fourth hepatectomies). Records retrospectively reviewed. primary tumor carcinoma colon in 26 rectum 16 patients. Liver metastases synchronous 24 (57.1%). Results There 25 men 17 women with mean age 63.5 years (range: 34–80). There no intraoperative or postoperative mortality. morbidity rates 9.5%, 14.3%, 18.2% (P = 0.6) respectively after first, third hepatectomies. No needed reoperation. Operative duration longer second hepatectomie than first without difference operative bleeding. Overall 5-year survivals 33%, 21%, 36% Factors prognostic on univariate analysis included serum carcinoembryonic antigen levels (P = 0.01) during hepatectomy, presence extrahepatic disease (P = 0.05) size larger 5 cm (P = 0.04) hepatectomie. Conclusions Repeat provide long-term survival similar those J. Surg. Oncol. 2006;93:1–7. © 2005 Wiley-Liss, Inc.