摘要: Lactide-based low molecular weight copolymers were synthesized and investigated as tissue adhesives. The oligomers composed of di or trifunctional central connecting segments lateral PLA blocks. Copolymers with glass transition temperatures in the 20–25 °C range, found to perform better. Strong connection was between length blocks, temperature (Tg) Adhesive Failure Strength different materials. Flexible e-caprolactone (CL) molecules inserted into produce longer biodegradable chains improve adhesive strength oligomers, while keeping their Tg within appropriate interval. Branched consisting a trimethylolpropane molecule three LA–CL segments, displayed enhanced vitro properties.
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