Niche-Specific Impact of a Symbiotic Function on the Persistence of Microbial Symbionts within a Natural Host.

摘要: ABSTRACT How the function of microbial symbionts is affected by their population/consortium structure within a host remains poorly understood. The symbiosis established between Euprymna scolopes and Vibrio fischeri well-characterized host-microbe association in which V. populations are known: produce bioluminescence from distinct crypt spaces dedicated called light organ. Previous studies have revealed that luminescence required for to persist organ deletion lux gene locus, responsible fischeri, leads persistence defect. In this study, we investigated impact on population We report defect specific I, most developmentally mature space nascent This result provides insight into structure/function relationship will be useful future mechanistic squid-Vibrio symbiosis. addition, our highlights potential developmental program spatiotemporal dynamics interactions. IMPORTANCE Metazoan development physiology depend microbes. symbiotic microbes spatial environment Here demonstrate, using binary symbiosis, requirement symbiont restricted environment. Our results also suggest link may fundamental aspect more complex