El origen de la variabilidad genética de los virus de la influenza

摘要: To better understand the significant variability displayed by influenza viruses, we need to be aware not only of its genetic characteristics, but also effect this makeup has on proteins associated with viral replication and antigenicity. The origin such diversity is due first foremost segmented genome that allows segment reassortment (antigenic shift) second error prone polymerase drift) responsible copying genes enclosed in these segments. These two combined mechanisms confer a plasticity often leads emergence new viruses nature.