Pathological Examination of Radical Prostatectomy Specimens in Men with Very Low Risk Disease at Biopsy Reveals Distinct Zonal Distribution of Cancer in Black American Men
作者： Debasish Sundi , Oleksandr N. Kryvenko , H. Ballentine Carter , Ashley E. Ross , Jonathan I. Epstein
DOI: 10.1016/J.JURO.2013.06.021
关键词:
摘要: Purpose: Of men with very low risk prostate cancer at biopsy recent evidence shows that black American are greater for adverse oncologic outcomes after radical prostatectomy. We studied prostatectomy specimens from and white to determine whether there systematic pathological differences.Materials Methods: Radical were evaluated in National Comprehensive Cancer Network® (NCCN) cancer. At diagnosis all underwent extended sampling (10 or more cores) treated the modern Gleason grade era. analyzed tumor volume, location 87 89 men. For each specimen dominant nodule was defined as largest highest grade.Results: Compared men, likely have significant (61% vs 29%), 7 (37% 11%, p <0.001) a volume of than 0.5 cm3 (45% 21%, = 0.001). Dominant...
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