Bacteria engineered to treat disorders in which trimethylamine (tma) is detrimental
作者： Dean Falb , Paul F. Miller , Vincent M. Isabella , Jonathan W. Kotula
DOI:
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摘要: The present invention provides recombinant bacterial cells comprising gene sequence encoding one or more trimethylamine catabolism enzyme(s). optionally comprise TMA and/or TMAO transporter(s). further pharmaceutical compositions the bacteria, and methods for treating disorders in which (TMA) is detrimental, such as cardiovascular disease, kidney trimethylaminuria, using of invention.
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