作者: Kenneth R. St. John , Lyle D. Zardiackas , Robert A. Poggie
DOI: 10.1002/JBM.B.10053
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摘要: Wear of the polyethylene in total joint prostheses has been a source morbidity and early device failure, which extensively reported last 20 years. Although research continues to attempt reduce wear joint-bearing surfaces by modifications polymer processing, there is renewed interest use metal-on-metal bearing couples for hip prostheses. testing replacement systems involving couple metal or ceramic heads on polymeric acetabular components performed reported, but, until recently, little data published pin-on-disk hip-simulator studies combination metallic femoral head component with an cup composed same dissimilar metal. This study investigated vitro resistance two cobalt/chromium/molybdenum alloys, differed primarily carbon content, as potential alloys hip-bearing couple. The results showed that alloy higher (0.25%) content was more resistant, this therefore chosen system, modeled loads motions might be exerted clinically. Comparison metal-on-polyethylene samples volumetric after 5,000,000 cycles 110–180 times metal-bearing Polyethylene particles retrieved from either lubricant simulator were characterized compared periprosthetic tissues other researchers, found similar. Based upon study, manufactured high cobalt/chromium hold sufficient promise justify human clinical trials. © 2003 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 68B: 1–14, 2004