A comparison of urinary tract pathology and morbidity in adult populations from endemic and non-endemic zones for urinary schistosomiasis on Unguja Island, Zanzibar.

摘要: Background: Renal tract involvement is implicated in both early and late schistosomiasis leading to increased disease burden. Despite there being good estimates of burden due renal secondary at the global level, it often difficult translate these into local communities. The aim this study was assess urinary pathology morbidity Zanzibar identify reliable clinical predictors associated disease. Methods: A cross-sectional comparison Ungujan men women living within either high or low endemic areas for conducted. Using urine analysis with reagent strips, parasitological egg counts, portable ultrasonography a qualitative case-history questionnaire. Data used single multiple predictor variable logistic regression. Results: One hundred sixty people were examined area (63% 37% men), 101 (61% 39% men). In area, egg-patent much more common (p = 1 × 10 -3 , 8 -6 respectively) area. Self-reported frothy urine, self-reported haematuria, dysuria urgency urinate 1.8 10-2, p 1.1 10-4, 1.3 10-6, 10-7, as assessed by ultrasonography. multi-variable regression model, self-reporting past year, having an egg-positive sample all independently detectable abnormality, consistent schistosomiasis-specific Having two features moderately sensitive (70%) abnormality specificity (92%).