Phase Angle and the Diagnosis of Impending Death in Patients with Advanced Cancer: Preliminary Findings

摘要: BACKGROUND Phase angle is a prognostic factor in patients with months of survival, but its accuracy has not been examined weeks/days survival. We determined the association between phase and survival advanced cancer admitted to an acute palliative care unit (APCU). SUBJECTS, MATERIALS, AND METHODS prospectively assessed consecutive our APCU. conducted univariate multivariate analyses adjusting for established factors. Post hoc subgroup without edema. RESULTS Among 204 patients, median overall was 10 days (95% confidence interval [CI] 8-11 days). Seventy-four (36%) did have The 3.7° entire cohort, 3.9° nonedematous 3.6° edematous subgroup. In analysis, low associated decreased cohort (≤3° vs. >3°, 7 days, p = .045) (5 18 < .001) (9 9 .84). reach significance remained significant (hazard ratio 2.46, 95% CI 1.14-5.31, .001). Specifically, ≤3° had 86% 77%-93%) 3-day CONCLUSION limited utility unselected APCU Further studies are required confirm these preliminary findings. IMPLICATIONS FOR PRACTICE this prospective study involving cancer, as measured by bioelectric impedance analysis predictor mortality independent known factors edema edema, which may inform diagnosis impending death potentially end-of-life decision making.