Cholesterol ester transfer protein, apolipoprotein E and lipoprotein lipase genotypes in patients with coronary artery disease in the Turkish population.
作者： T Isbir , H Yilmaz , B Agachan , ZE Karaali , None
DOI: 10.1034/J.1399-0004.2003.00137.X
关键词:
摘要: The aim of this study was to compare patients with coronary artery disease (CAD) healthy objects, in order explore a possible association between CAD and the variants gene encoding cholesterol ester transfer protein (CETP), apolipoprotein E (Apo E) lipoprotein lipase (LPL). relationship CETP MspI, apo LPL PvuII polymorphisms serum lipids were investigated 173 111 controls. frequency Apo epsilon4 (p < 0.05) M1 0.01) alleles higher group than control group. In group, those Msp allele had levels total (TC) = 0026) low-density (LDL-C) M2 allele. Subjects an epsilon2 lowest TC LDL-C, while subjects highest. CETP, associated level high-density (HDL-C) 0.012) distributions genotype did not differ groups. present demonstrates that Msp1 are variations controls Turkish population.
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