Higher blood pressure in normal weight women with PCOS compared to controls
作者： Jan Roar Mellembakken , Azita Mahmoudan , Lars Mørkrid , Inger Sundström-Poromaa , Laure Morin-Papunen
DOI: 10.1530/EC-20-0527
关键词:
摘要: Objective Obesity is considered to be the strongest predictive factor for cardio-metabolic risk in women with polycystic ovary syndrome (PCOS). The aim of study was compare blood pressure (BP) normal weight PCOS and controls matched age BMI. Methods From a Nordic cross-sectional base 2615 individuals ethnicity, we studied sub cohort 793 BMI < 25 kg/m2 (512 according Rotterdam criteria 281 BMI-matched controls). Participants underwent measurement BP body composition (BMI, waist-hip ratio), lipid status, fasting BG. Data were presented as median (quartiles). Results 28 (25, 32) years 22.2 (20.7, 23.4) kg/m2. Systolic 118 (109, 128) mmHg compared 110 (105, 120) diastolic 74 (67, 81) vs 70 (64, 75) mmHg, both P 0.001. prevalence ≥ 140/90 11.1% (57/512) 1.8% (5/281) controls, In 35 comparable (12.7% 9.8%, = 0.6). Using multiple regression analyses, association found age, waist circumference, total cholesterol PCOS. Conclusions Normal have higher than controls. metabolic screening are relevant also young
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sci-hub.st 参考文章(40)
Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. The Lancet. ,vol. 360, pp. 1903- 1913 ,(2002) , 10.1016/S0140-6736(02)11911-8
Ishwarlal Jialal, A Practical Approach to the Laboratory Diagnosis of Dyslipidemia American Journal of Clinical Pathology. ,vol. 106, pp. 128- 138 ,(1996) , 10.1093/AJCP/106.1.128
S. S. Lim, R. J. Norman, M. J. Davies, L. J. Moran, The effect of obesity on polycystic ovary syndrome: a systematic review and meta-analysis Obesity Reviews. ,vol. 14, pp. 95- 109 ,(2013) , 10.1111/J.1467-789X.2012.01053.X
Gerard Conway, Didier Dewailly, Evanthia Diamanti-Kandarakis, Héctor F Escobar-Morreale, Stephen Franks, Alessandra Gambineri, Fahrettin Kelestimur, Djuro Macut, Dragan Micic, Renato Pasquali, Marija Pfeifer, Duarte Pignatelli, Michel Pugeat, Bulent O Yildiz, The polycystic ovary syndrome: a position statement from the European Society of Endocrinology European Journal of Endocrinology. ,vol. 171, pp. 1- 29 ,(2014) , 10.1530/EJE-14-0253
Agnieszka Zachurzok-Buczynska, Leslaw Szydlowski, Aneta Gawlik, Krzysztof Wilk, Ewa Malecka-Tendera, Blood pressure regulation and resting heart rate abnormalities in adolescent girls with polycystic ovary syndrome. Fertility and Sterility. ,vol. 96, pp. 1519- 1525 ,(2011) , 10.1016/J.FERTNSTERT.2011.09.043
Dorte Glintborg, Katrine Hass Rubin, Mads Nybo, Bo Abrahamsen, Marianne Andersen, None, Morbidity and medicine prescriptions in a nationwide Danish population of patients diagnosed with polycystic ovary syndrome European Journal of Endocrinology. ,vol. 172, pp. 627- 638 ,(2015) , 10.1530/EJE-14-1108
Kay-Tee Khaw, Nicholas Wareham, Sheila Bingham, Robert Luben, Ailsa Welch, Nicholas Day, Association of Hemoglobin A1c with Cardiovascular Disease and Mortality in Adults: The European Prospective Investigation into Cancer in Norfolk Annals of Internal Medicine. ,vol. 141, pp. 413- 420 ,(2004) , 10.7326/0003-4819-141-6-200409210-00006
Zhiping Huang, Walter C Willett, JoAnn E Manson, Bernard Rosner, Meir J Stampfer, Frank E Speizer, Graham A Colditz, Body Weight, Weight Change, and Risk for Hypertension in Women Annals of Internal Medicine. ,vol. 128, pp. 81- 88 ,(1998) , 10.7326/0003-4819-128-2-199801150-00001
J. Holte, G. Gennarelli, C. Berne, T. Bergh, H. Lithell, Elevated ambulatory day-time blood pressure in women with polycystic ovary syndrome: a sign of a pre-hypertensive state? Human Reproduction. ,vol. 11, pp. 23- 28 ,(1996) , 10.1093/OXFORDJOURNALS.HUMREP.A019028
LP Cheung, RCW Ma, PM Lam, IH Lok, CJ Haines, WY So, PCY Tong, CS Cockram, CC Chow, WB Goggins, None, Cardiovascular risks and metabolic syndrome in Hong Kong Chinese women with polycystic ovary syndrome Human Reproduction. ,vol. 23, pp. 1431- 1438 ,(2008) , 10.1093/HUMREP/DEN090