Atypical pyruvate kinase in a patient with haemolytic anaemia.

作者: N. J. Brandt , H. K. Hanel

DOI: 10.1111/J.1600-0609.1971.TB01963.X

关键词:

摘要: In a case of hereditary nonspherocytic haemolytic anaemia an atypical erythrocyte pyruvate kinase was found. The characterized as on the basis following biochemical parameters which differed from those normal enzyme: Michaelis' constant, thermostability, pH dependency, urea inhibition, and electrophoretic mobility. The results indicate that there may be structural difference between kinase.

参考文章(7)
Donald E. Paglia, William N. Valentine, Marjorie A. Baughan, Denis R. Miller, Claude F. Reed, O. Ross McIntyre, An inherited molecular lesion of erythrocyte pyruvate kinase Journal of Clinical Investigation. ,vol. 47, pp. 1929- 1946 ,(1968) , 10.1172/JCI105883
H.K. Hanel, N.J. Brandt, HÆMOLYTIC ANÆMIA DUE TO ABNORMAL PYRUVATE KINASE The Lancet. ,vol. 292, pp. 113- ,(1968) , 10.1016/S0140-6736(68)90403-0
K.G Blume, G.W Löhr, H.W Rüdiger, A Schalhorn, PYRUVATE KINASE IN HUMAN ERYTHROCYTES The Lancet. ,vol. 291, pp. 529- 530 ,(1968) , 10.1016/S0140-6736(68)91494-3
Henrik Olesen, Poul O. Pedersen, J. Brunvoll, G. Hagen, Jaakko Paasivirta, Gel filtration of albumin on sephadex g-200 in urea. Acta Chemica Scandinavica. ,vol. 22, pp. 1386- 1394 ,(1968) , 10.3891/ACTA.CHEM.SCAND.22-1386
H. K. Hanel, Pyruvate kinase in human erythrocytes. Scandinavian Journal of Haematology. ,vol. 6, pp. 173- 174 ,(2009) , 10.1111/J.1600-0609.1969.TB01822.X
H. K. Hanel, B. Harvald, G. Mor, N. Christensen, T. Deckert, A case of haemolytic anaemia due to pyruvate kinase deficiency. Scandinavian Journal of Haematology. ,vol. 4, pp. 53- 60 ,(2009) , 10.1111/J.1600-0609.1967.TB01598.X