Nicotine induces long-lasting potentiation in the dentate gyrus of nicotine-primed rats
作者： Shabaz Hamid , Gavin S Dawe , Jeffrey A Gray , John D Stephenson
DOI: 10.1016/S0168-0102(97)00074-6
关键词:
摘要: A challenge dose of nicotine (0.4 mg kg−1 s.c.) produced a long-lasting potentiation (LLP) field EPSPs evoked in the dentate gyrus by stimulation medial perforant path urethane-anaesthetized rats primed four weeks previously with seven daily injections (0.8 s.c.). The same did not alter saline vehicle. Systemic injection either mecamylamine or propranolol, 30 min before challenge, prevented induction LLP without affecting baseline but neither drug affected when given after it was established. Since nicotine-priming regime is known to increase tyrosine hydroxylase activity and hippocampal noradrenaline release response results suggest that systemic released sufficient nicotine-primed induce β-adrenoceptor-mediated LLP.
elsevier.com
sci-hub.se 参考文章(25)
S. Wonnacott, M. A. H. Russell, Ian P. Stolerman, Nicotine psychopharmacology : molecular, cellular, and behavioural aspects Oxford University Press. ,(1990)
LK Nisenbaum, MJ Zigmond, AF Sved, ED Abercrombie, Prior exposure to chronic stress results in enhanced synthesis and release of hippocampal norepinephrine in response to a novel stressor The Journal of Neuroscience. ,vol. 11, pp. 1478- 1484 ,(1991) , 10.1523/JNEUROSCI.11-05-01478.1991
Katherine M. Smith, Stephen N. Mitchell, Michael H. Joseph, Effects of chronic and subchronic nicotine on tyrosine hydroxylase activity in noradrenergic and dopaminergic neurones in the rat brain. Journal of Neurochemistry. ,vol. 57, pp. 1750- 1756 ,(1991) , 10.1111/J.1471-4159.1991.TB06377.X
Dennis Dahl, Jingmin Li, Induction of long-lasting potentiation by sequenced applications of isoproterenol. Neuroreport. ,vol. 5, pp. 657- 660 ,(1994) , 10.1097/00001756-199401000-00032
Edward C. Burgard, Gregory Decker, John M. Sarvey, NMDA receptor antagonists block norepinephrine-induced long-lasting potentiation and long-term potentiation in rat dentate gyrus. Brain Research. ,vol. 482, pp. 351- 355 ,(1989) , 10.1016/0006-8993(89)91199-2
S.N. Mitchell, K.M. Smith, M.H. Joseph, J.A. Gray, Increases in tyrosine hydroxylase messenger RNA in the locus coeruleus after a single dose of nicotine are followed by time-dependent increases in enzyme activity and noradrenaline release Neuroscience. ,vol. 56, pp. 989- 997 ,(1993) , 10.1016/0306-4522(93)90145-6
P.K. Stanton, I. Mody, U. Heinemann, A role for N-methyl-D-aspartate receptors in norepinephrine-induced long-lasting potentiation in the dentate gyrus. Experimental Brain Research. ,vol. 77, pp. 517- 530 ,(1989) , 10.1007/BF00249605
Zibin Chen, Göran Engberg, The rat nucleus paragigantocellularis as a relay station to mediate peripherally induced central effects of nicotine Neuroscience Letters. ,vol. 101, pp. 67- 71 ,(1989) , 10.1016/0304-3940(89)90442-4
E.D. Abercrombie, R.W. Keller, M.J. Zigmond, Characterization of hippocampal norepinephrine release as measured by microdialysis perfusion: Pharmacological and behavioral studies Neuroscience. ,vol. 27, pp. 897- 904 ,(1988) , 10.1016/0306-4522(88)90192-3
D. Dahl, J. M. Sarvey, Norepinephrine induces pathway-specific long-lasting potentiation and depression in the hippocampal dentate gyrus Proceedings of the National Academy of Sciences of the United States of America. ,vol. 86, pp. 4776- 4780 ,(1989) , 10.1073/PNAS.86.12.4776