Acute Moderate Exercise Does Not Further Alter the Autonomic Nervous System Activity in Patients with Sickle Cell Anemia

摘要: A decreased global autonomic nervous system (ANS) activity and increased sympathetic activation in patients with sickle cell anemia (SCA) seem to worsen the clinical severity could play a role pathophysiology of disease, notably by triggering vaso-occlusive crises. Because exercise challenges ANS general population, we sought determine whether short (<15 min) progressive moderate session conducted until first ventilatory threshold had an effect on group SCA healthy individuals (CONT group). Temporal spectral analyses nocturnal heart rate variability were performed before 3 nights following session. Standard deviation all normal RR intervals (SDNN), total power, low frequencies (LF) high powers (HF) lower but LF/HF was higher than CONT group. Moderate did not modify both groups. In addition, no adverse events occurred during entire protocol. These results imply that this kind is detrimental for patients.