摘要: Cavitation was first directly related to mechanical heart valves in the mid 1980s after a series of valve failures observed with Edwards–Duromedics valve. The damages indicated that cavitation could be responsible. Later, several vitro studies visualized bubble formation and collapse at valves. It suggested also cause damage formed elements blood thereby enhance risk thromboembolic complications seen patients. Therefore, an applicable technique for vivo detection is required. This article reviews techniques developed suggests focus future studies.