Non-Vitamin K Antagonist Oral Anticoagulants in Atrial Fibrillation
作者： Anna Plitt , Christian T. Ruff , Robert P. Giugliano
DOI: 10.1016/J.HOC.2016.05.002
关键词:
摘要: For more than 50 years, vitamin K antagonists (VKAs) have been the standard of care for treatment atrial fibrillation (AF). However, numerous limitations VKAs led to development non-VKA oral anticoagulants (NOACs). There are 4 NOACs currently approved prevention thromboembolism in patients with nonvalvular AF. This article provides an overview AF, summarizes basic properties NOACs, and reviews landmark trials. Current data on use special populations specific clinical scenarios also presented. Lastly, recommendations from experts controversial topics bleeding management reversal described.
elsevier.com
sci-hub.se 参考文章(55)
Pamela Nerheim, Sally Birger-Botkin, Lubna Piracha, Brian Olshansky, Heart Failure and Sudden Death in Patients With Tachycardia-Induced Cardiomyopathy and Recurrent Tachycardia Circulation. ,vol. 110, pp. 247- 252 ,(2004) , 10.1161/01.CIR.0000135472.28234.CC
Edith Nutescu, Kim A. Williams, Richard J. Kovacs, Greg C. Flaker, Sherry J. Saxonhouse, John U. Doherty, Kim K. Birtcher, Adam Cuker, Bruce L. Davidson, Robert P. Giugliano, Christopher B. Granger, Amir K. Jaffer, Bella H. Mehta, Practical management of anticoagulation in patients with atrial fibrillation. Journal of the American College of Cardiology. ,vol. 65, pp. 1340- 1360 ,(2015) , 10.1016/J.JACC.2015.01.049
Ammar Majeed, Sam Schulman, Bleeding and antidotes in new oral anticoagulants Best Practice & Research Clinical Haematology. ,vol. 26, pp. 191- 202 ,(2013) , 10.1016/J.BEHA.2013.07.001
Stanley Nattel, Denis Chartier, Tae-Joon Cha, Joachim R. Ehrlich, Stefan H. Hohnloser, Liming Zhang, Peter Melnyk, Peter Melnyk, Cellular electrophysiology of canine pulmonary vein cardiomyocytes: action potential and ionic current properties The Journal of Physiology. ,vol. 551, pp. 801- 813 ,(2003) , 10.1111/J.1469-7793.2003.00801.X
Christian T Ruff, Robert P Giugliano, Eugene Braunwald, Elliott M Antman, New oral anticoagulants in patients with atrial fibrillation – Authors'reply The Lancet. ,vol. 384, pp. 25- 26 ,(2014) , 10.1016/S0140-6736(14)61106-5
Robert P Giugliano, Christian T Ruff, Eugene Braunwald, Sabina A Murphy, Stephen D Wiviott, Jonathan L Halperin, Albert L Waldo, Michael D Ezekowitz, Jeffrey I Weitz, Jindřich Špinar, Witold Ruzyllo, Mikhail Ruda, Yukihiro Koretsune, Joshua Betcher, Minggao Shi, Laura T Grip, Shirali P Patel, Indravadan Patel, James J Hanyok, Michele Mercuri, Elliott M Antman, None, Edoxaban versus warfarin in patients with atrial fibrillation The New England Journal of Medicine. ,vol. 369, pp. 2093- 2104 ,(2013) , 10.1056/NEJMOA1310907
Manesh R Patel, Kenneth W Mahaffey, Jyotsna Garg, Guohua Pan, Daniel E Singer, Werner Hacke, Günter Breithardt, Jonathan L Halperin, Graeme J Hankey, Jonathan P Piccini, Richard C Becker, Christopher C Nessel, John F Paolini, Scott D Berkowitz, Keith AA Fox, Robert M Califf, Rocket AF Steering Committee, None, Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation The New England Journal of Medicine. ,vol. 365, pp. 883- 891 ,(2011) , 10.1056/NEJMOA1009638
Stuart J Connolly, Janice Pogue, John Eikelboom, Gregory Flaker, Patrick Commerford, Maria Grazia Franzosi, Jeffrey S Healey, Salim Yusuf, None, Benefit of Oral Anticoagulant Over Antiplatelet Therapy in Atrial Fibrillation Depends on the Quality of International Normalized Ratio Control Achieved by Centers and Countries as Measured by Time in Therapeutic Range Circulation. ,vol. 118, pp. 2029- 2037 ,(2008) , 10.1161/CIRCULATIONAHA.107.750000
Jonathan P Piccini, Susanna R Stevens, Yuliya Lokhnygina, Manesh R Patel, Jonathan L Halperin, Daniel E Singer, Graeme J Hankey, Werner Hacke, Richard C Becker, Christopher C Nessel, Kenneth W Mahaffey, Keith AA Fox, Robert M Califf, Günter Breithardt, ROCKET AF Steering Committee & Investigators, Outcomes After Cardioversion and Atrial Fibrillation Ablation in Patients Treated With Rivaroxaban and Warfarin in the ROCKET AF Trial Journal of the American College of Cardiology. ,vol. 61, pp. 1998- 2006 ,(2013) , 10.1016/J.JACC.2013.02.025
Joachim Stangier, Sebastian Haertter, Karl-Heinz Liesenfeld, Wolfgang Wienen, Martin Feuring, Andreas Clemens, Joanne van Ryn, Dabigatran etexilate - a novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity Thrombosis and Haemostasis. ,vol. 103, pp. 1116- 1127 ,(2010) , 10.1160/TH09-11-0758