Identification of 5-desmethylubiquinone-9 as an intermediate in the biosynthesis of ubiquinone-9 by rat liver mitochondria

作者: Robert M. Houser , Robert E. Olson

DOI: 10.1016/0024-3205(74)90428-7

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摘要: Abstract Radioactive 5-desmethylubiquinone-9 has been isolated from mitochondria synthesizing ubiquinone-9- 14 C p-hydroxybenzoate-U- C. By mass spectrometry, the natural shown to be identical with that chemically synthesized fumigatol and solanesol. Synthetic 5-desmethylubiquinone-9- 3 H can methylated by S-adenosyl-L-methionine in submitochondrial particles.

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