Novel antibacterial electrospun mats based on poly(d,l-lactide) nanofibers and zinc oxide nanoparticles

摘要: This investigation addresses the morphological, mechanical, and antibacterial evaluation of nanocomposite mats based on poly(d,l-lactide) nanofibers with different zinc oxide nanoparticles (nano-ZnO) concentration, that were elaborated by two techniques, i.e., electrospinning polymer/ZnO solutions combination polymer electrospraying nano-ZnO dispersions. The analysis precursory was carried out in order to understand achieved morphology nanofibers. obtained poly(d,l-lactide)/ZnO fibrous showed a uniform an average porosity ca. 55 % pore size around 45 μm. presence ZnO increased toughness mats, optimal concentration (i.e., 3 wt%) observed at which tensile strength Young’s modulus could be improved. Concerning properties, relatively low provoked growth inhibition Gram-negative Escherichia coli Gram-positive Staphylococcus aureus bacteria. have potential features for use as antimicrobial wound dressings.