The N-terminal sequence of the heavy chain of rabbit immunoglobulin IgG.

作者: JM Wilkinson , EM Press , RR Porter

DOI: 10.1042/BJ1000303

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摘要: The absence of an N-terminal amino acid with a free alpha-amino group from the heavy chain rabbit immunoglobulin IgG has been confirmed and no evidence could be found blocking formyl, acetyl or propionyl group. appears to pyrrolid-2-one-5-carboxylic (PCA) in all molecules. A mixed sequence follows approximate proportions: PCA-Ser-Val-Glu-Glu-Ser-Gly-Gly-Arg, 50%; PCA-Ser-Leu-Glu, 20%; PCA-Glu(NH(2)), 20%. chains purified antibody, namely anti-(human serum albumin), homozygous at allotypic loci both showed similar sequence.

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