Fine-needle aspiration biopsy of high-grade sarcoma: a report of 107 cases.

摘要: BACKGROUND. To the authors' knowledge, few studies exist demonstrating reliability of fine-needle aspiration (FNA) biopsy for high-grade sarcoma (HGS). METHODS. In current study, authors reviewed their cytopathology database (March 2001 through January 2007) and identified all FNA cases diagnosed as HGS. They also searched tissue HGS that had prior findings. RESULTS. A total 107 samples from 98 patients (age range, 13–90 years, with a male:female ratio 1:1) an diagnosis HGS, or another entity. Ten were nondiagnostic. Of 97 remaining samples, 6 something other than (sensitivity 94%). The positive predictive value was 97% (88 91 cases). Fifty-four not otherwise specified, 8 myxofibrosarcoma, osteosarcoma, 5 malignant peripheral nerve sheath tumor, leiomyosarcoma, 4 Ewing sarcoma, liposarcoma, 2 epithelioid 1 angiosarcoma. Approximately 71% presented primary 23% disease recurrence, 7% metastasis. Sites included lower extremity (59%), upper (19%), trunk (15%), groin (4%), head neck (4%). confirmed histologically in 88% cases, clinically cytogenetically 1% cases; 3% false-positive results patient lost to follow-up. Sixteen 19 received neoadjuvant chemotherapy based on alone. CONCLUSIONS. A cytopathologic found be accurate 88 (91%) A appears reliable high percentage when used close conjunction orthopedic team. Cancer (Cancer Cytopathol) 2007. © 2007 American Society.