The effect of regeneration of the growth potentialities in vitro of rat liver at different ages.

作者: André D. Glinos , Eleanor G. Bartlett

DOI:

关键词:

摘要: Summary 1.The growth potential of normal rat liver was tested by means the tissue culture method. Under experimental conditions used, found to be an inverse proportional function age animal. 2.The regenerating independent animal and same order magnitude as that young animals. 3.The restorative effect regeneration on old animals outlasted regenerative process itself still apparent 1 month after completion regeneration. 4.Differences in morphology organization colonies at different ages were described their relationship considered. 5.The significance these results with respect general physiology carcinogenesis discussed.

参考文章(20)
M. J. Shear, Nathaniel Shear, Samuel Cabot, Adrien Perrault, Studies in carcinogenesis: XI. Development of skin tumors in mice painted with 3:4-benzpyrene and creosote oil fractions. American Journal of Pathology. ,vol. 16, pp. 301- 312 ,(1940)
George O. Gey, An Improved Technic for Massive Tissue Culture American Journal of Cancer. ,vol. 17, pp. 752- 756 ,(1933) , 10.1158/AJC.1933.752
Max J. A. Des Ligneris, Precancer and Carcinogenesis American Journal of Cancer. ,vol. 40, pp. 1- 46 ,(1940) , 10.1158/AJC.1940.1
Nancy L. R. Bucher, André D. Glinos, The Effect of Age on Regeneration of Rat Liver Cancer Research. ,vol. 10, pp. 324- 332 ,(1950)
William F. Friedewald, Peyton Rous, THE INITIATING AND PROMOTING ELEMENTS IN TUMOR PRODUCTION Journal of Experimental Medicine. ,vol. 80, pp. 101- 126 ,(1944) , 10.1084/JEM.80.2.101
J. C. Mottram, A developing factor in experimental blastogenesis The Journal of Pathology and Bacteriology. ,vol. 56, pp. 181- 187 ,(1944) , 10.1002/PATH.1700560207
Charles Zeleny, Some experiments on the effect of age upon the rate of regeneration Journal of Experimental Zoology. ,vol. 7, pp. 563- 593 ,(1909) , 10.1002/JEZ.1400070307
B. D. Pullinger, An experimental approach to the problem of trauma and tumours The Journal of Pathology and Bacteriology. ,vol. 57, pp. 467- 476 ,(1945) , 10.1002/PATH.1700570410
Ian MacKenzie, Peyton Rous, THE EXPERIMENTAL DISCLOSURE OF LATENT NEOPLASTIC CHANGES IN TARRED SKIN. Journal of Experimental Medicine. ,vol. 73, pp. 391- 416 ,(1941) , 10.1084/JEM.73.3.391