Clinical implications of measuring prolactin levels in males of infertile couples

摘要: Although in females of infertile couples abnormal prolactin (PRL) has a definitive role the medical flowchart, its males is less clear. Animal models suggest that PRL does not play major male reproduction, although trophic action on accessory glands was often observed. Studies humans are scanty. We systematically evaluated possible clinical and ultrasound correlates couples. Of 288 consecutive couples, 269 (36.6 ± 4.4 years) without genetic abnormalities were studied. All men underwent physical, biochemical, seminal evaluation scrotal transrectal before after ejaculation. Ejaculatory erectile functions assessed by Premature Ejaculation Diagnostic Tool (PEDT) International Index Erectile Function (IIEF)-15 respectively; prostate-related symptoms National Institutes Health-Chronic Prostatitis Symptom Prostate Score; psychological Middlesex Hospital Questionnaire. Among semen parameters, only positive association between ejaculate volume significant, even adjusting for age, total testosterone thyroid-stimulating hormone (adj. r = 0.126, p < 0.05). In logistic ordinal model, aforementioned confounders volume, negatively associated with delaying ejaculation according to PEDT#1 score (Wald = 4.65, an age- volume-adjusted, iterative binary low fivefold risk any failure controlling (HR = 5.15 [1.15-23], features, we found significant vesicles (SV) inhomogeneity, ejaculation, deferential ampullas diameter. Associations confirmed nested 1 : 1 case-control analysis. No associations other parameters. For first time, this study extends concept effect from animals humans. report among SV Low lessened ability control