Photodynamic action of bonellin, an integumentary chlorin of Bonellia viridis, Rolando (Echiura, Bonelliidae).

作者: L. Agius , V. Jaccarini , J.A. Ballantine , V. Ferrito , A. Pelter

DOI: 10.1016/0305-0491(79)90242-6

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摘要: 1. The photodynamic activity of bonellin, an integumentary chlorin Bonellia viridis, is investigated. 2. 10(-6) M bonellin solutions haemolyze erythrocytes only in the presence light. Previous illumination (tungsten lamp 2000-4000 lux for 1 hr) does not affect results. Under lowered oxygen tensions bioactivity depressed. Benzoquinone and singlet quenchers delay effect. 3. Bonellin (2 x M) destroys echinoid gamete function, depresses uptake spermatozoa, arrests development eggs. These effects are produced 4. Copper photodynamically active. role copper may be to protect against photosensitization.

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