Radiation treatment for medulloblastoma. A 21-year review.

摘要: ✓ One hundred and twenty-two patients with medulloblastoma received postoperative irradiation at the Princess Margaret Hospital, Toronto, from 1958 to 1978, inclusive. The surgical procedure in these was total resection (44 patients), subtotal (66 or biopsy alone (12 patients). Twenty-five adjuvant chemotherapy. Overall 5- 10-year survival rates were 56% 43%, respectively. Improved associated an increased degree of posterior fossa radiation doses 5200 rads more. common site first relapse (in 56 patients, 46%). Systemic metastases occurred 18 52 (35%), use ventriculosystemic shunts. Millipore filters did not prevent systemic shunted patients. A subset 15 who a dose more after had 5-year rate 77%, which remained con...