Screening for human immunodeficiency virus (HIV) dementia in an HIV clade C-infected population in India.

摘要: Although human immunodeficiency virus (HIV) clade C infects the largest populations worldwide, to date there are no prospective studies reported thus far determine incidence or prevalence of HIV dementia in this population. is a CCR5-tropic and predominantly macrophages, which key cells implicated pathogenesis dementia. However, has only rarely been these populations. The authors used recently developed International Dementia Scale (IHDS) screen well-characterized cohort HIV-infected discordant couples Pune, India. 48 HIV+ subjects with CD4 cell count <200 cells/mm3 HIV− were studied. had significantly lower IHDS scores compared subjects. 35% 15% scored <10 on IHDS. These observations suggest that may be higher population than previously reported. More importantly, it demonstrates can as screening tool Indian