Syntheses employing pyridyllithium reagents: new routes to 2,6-disubstituted pyridines and 6,6′-disubstituted 2,2′-bipyridyls

作者: J.E. Parks , B.E. Wagner , R.H. Holm

DOI: 10.1016/S0022-328X(00)89953-2

关键词:

摘要: New 2,6-disubstituted pyridine derivatives have been synthesized employing 6-bromo-2-lithiopyridine as an intermediate. Subsequent replacement of the 6-bromine can be effected by …

参考文章(21)
J. E. Parks, Burkhard E. Wagner, Richard H. Holm, Three-dimensional macrocyclic encapsulation reactions. I. Synthesis of six-coordinate complexes with nonoctahedral stereochemistry Journal of the American Chemical Society. ,vol. 92, pp. 3500- 3502 ,(1970) , 10.1021/JA00714A064
George M. Whitesides, William F. Fischer, Joseph San Filippo, Robert W. Bashe, Herbert O. House, Reaction of lithium dialkyl- and diarylcuprates with organic halides Journal of the American Chemical Society. ,vol. 91, pp. 4871- 4882 ,(1969) , 10.1021/JA01045A049
Henry Gilman, Frank K. Cartledge, See-Yuen Sim, The analysis of organic-substituted group IVB lithium compounds Journal of Organometallic Chemistry. ,vol. 1, pp. 8- 14 ,(1963) , 10.1016/S0022-328X(00)80039-X
Gideon Fraenkel, Shlomo Dayagi, Sadao Kobayashi, Nuclear magnetic resonance and ultraviolet spectroscopy of substituted aromatic organometallic compounds of lithium, magnesium, and calcium The Journal of Physical Chemistry. ,vol. 72, pp. 953- 961 ,(1968) , 10.1021/J100849A028
George M. Whitesides, Charles P. Casey, Jeanne K. Krieger, Thermal decomposition of vinylic copper(I) and silver(I) organometallic compounds Journal of the American Chemical Society. ,vol. 93, pp. 1379- 1389 ,(1971) , 10.1021/JA00735A011
T. A. GEISSMAN, MAURICE J. SCHLATTER, IRVING D. WEBB, JOHN D. ROBERTS, The synthesis of some intermediates for use in the preparation of analogs of salicylaldehyde ethylenediimine cobalt (salcomine). Journal of Organic Chemistry. ,vol. 11, pp. 741- 750 ,(1946) , 10.1021/JO01176A015
Frank H. Pinkerton, Shelby F. Thames, Organosilicon compounds. VIII. Cleavage of the silicon‐carbon bond in 2‐(trimethylsilyl)pyridine with benzaldehyde Journal of Heterocyclic Chemistry. ,vol. 6, pp. 433- 433 ,(1969) , 10.1002/JHET.5570060330